MODE OF PURGATIVE ACTION OF KUTAKI (PICRORHIZA KURROA)-A CHEMICAL ASSAY
Kutaki is aa well known purgative drug having Bhedana action according to Ayurveda due to which it facilitates penetration into fecal mass so that even very hard feces is softened. This study was carried out to understand the Bhedana action of the drug from modern pharmacological point of view. The results of this study showed that Kutaki possesses surface tension reducing action. It neither contains anthroquinone nor possesses swelling action. In vitro study showed that it is nonirritant purgative drug.
Key Words: Kutaki, Katuki. Picrorhiza kurroa, Surface tension reducing Â Â Â
Fairbairn, J.W. (1942): Quantitative method of measuring the anthraquinone. Pharm. J. 148,198.
Goodman , L.S. and Gilman, A (1970): The pharmacological basis of therapeutics.IV Edition, 1020-30. The Macmilan Comp., London.
Krantz J.C. and Carr, G.J. (1967): Experimental Pharmacologic principles of medical practice. 6th Edition, II Reprint. Indian Edition Scientific Book Agency,Calcutta.
Sharngdhara: Sharngdhara Samhita, Purvkhanda 4:5 Krishnadasa axadami Varanasi
Singh, Gurdip and Chaturvedi, G.N. (1976): Studies on Virechana with special reference to cathartic effect of Kutaki (Picrorhiza kurrooa Royle ex Benth.). Ph.D. Thesis, Institute of Medical Sciences, BHU, Varanasi
Skyrime E.W. and Wallis, T.E. (1936): Psyllium, Ispaghula and related seeds.Quart. J. Pharm.Pharmacol, 9, 198.