SURFACTANT EFFECT OF ALCOHOLIC EXTRACT OF KUTAKI (PICRORHIZA KURROA)-CHEMICAL ASSAY

  • Gurdip Singh

Abstract

Gurdip and Chaturvedi (2016) carried out a detailed chemical assay for ascertaining the Bhedana action of Kutaki and showed that the purgative action of the powder of this drug is due to its surface tension reducing action. The present study was planned further to evaluate the surface tension reducing of whole alcoholic extract of Kutaki (Picrorhiza kurroa) quantitatively. The results of this study showed that whole alcoholic extract of Kutaki possesses significant surface tension reducing action. It also significantly increased the de-emulsification which further confirms its surface tension reducing action.

Keu Words: Whole alcoholic extract of Kutaki/Katuki. Picrorhiza kurroa, Surface-active agent, surfactant, de-emulsification

References

Bhava prakasha, Vol. I & II Chaukhamba Sanskrit Seroies, Varanasi, 1969.

Goodman , L.S. and Gilman, A (1970): The pharmacological basis of therapeutics.IV Edition, 1020-30. The Macmilan Comp., London.

Gurdip Singh and Chaturvedi G. N. (2016): Mode of Purgative Action of Kutaki (Picrorhiza kurroa)-A Chemical Assay. JAPS 3 (3)

Kitagava I., Hino K., Nishimura T., Iwata, E., and Yosiaka, I. (1971): Constituents of Picrorhiza kurrooa I. Structure of picroside I bitter principle of Subtrranean part. Chem.Pharm. Bull. 19 (12),2534-44.

Kitagava I., Hino K., Nishimura T., Mukai E. and, Yosioka I., (1969) : Picroside-1 a bitter principle of Picrorhiza kurrooa . Tetrahedron Lett. 43, 3837-40

Kloss P. and Schwabe, W. (1973): Liver protecting and choleratic Picroside-II from Picrorhiza kurrooa. Chem. Abst., Vol. 79 (July-Dec.,1973), P 108054 r.

Krantz J.C. and Carr, G.J. (1967): Experimental Pharmacologic principles of medical practice. 6th Edition, II Reprint. Indian Edition Scientific Book Agency,Calcutta.

Sharngdhara: Sharngdhara Samhita, Purvkhanda 4:5 Krishnadasa axadami Varanasi

Singh B. and Rastogi, R. P. (1972): Chemical examination of Picrorhiza kurrooa Benth. Part IV-reinvestigation of kutkin. Indian J. Chem. 10 (1), 29-31.

Singh, Gurdip and Chaturvedi, G.N. (1976): Studies on Virechana with special reference to cathartic effect of Kutaki (Picrorhiza kurrooa Royle ex Benth.). Ph.D. Thesis, Institute of Medical Sciences, BHU, Varanasi

Skyrime E.W. and Wallis, T.E. (1936): Psyllium, Ispaghula and related seeds. Quart. J. Pharm.Pharmacol, 9, 198.

Stecher,P.G., Finkel,M.J., Siegmund,G.H. and Szfrenski DM (1960): The Marck index of chemical and drugs. 7th Edition, 377; Marck & Co., Inc. Pahway, USA.

Weinges, K., Kless P. and Henkels (1972): Natural products from medicinal plants XVII Picroside-II, a new 6-Vanilloyl catalpol from Picrorhiza kurrooa. J. Ustus. Liebigs Ann..Chem.759; 173-82. Chem. Abst. Vol. 77. 137533 K.

Published
2017-05-18