A Study on Role of Kapikacchu (Mucuna pruriens) in Management of Parkinson's Disease

Sanjay Dhruve, Gurdip Singh

Abstract


Kapikcchu (Mucuna pruriens) has been reported to have L-dopa, which is nowadays prescribed for the treatment of Parkinson's disease, hence seeds of Kapikacchu were selected to evaluate its role in the management of Parkinson's disease (Kampavata). Powder of its seeds was administered in the dose of 6 gm thrice a day with water for 45 days. The results of this study showed that Kapikcchu (Mucuna pruriens) provided significant relief in signs and symptoms of the disease and clinical parameters. It significantly corrected the movement disorders of the patients. After the treatment 50% patients got marked improvement, 37.5% improvement and 12.5% patients remained stable.  

Keywords: Parkinson’s disease, Kampavata, Kapikacchu, Mucuna pruriens


Full Text:

PDF

References


• A.M.Bronstein, J.D.Hood, M.A.Gtesty, Christina panagi: Visual control of balance in Cerebellar and parkinsonian syndrome Annual of Neurology - 1982. Agid V. and Javoy Agid F: Peptides and Parkinson's disease.Trends in neuroscience, 8: 30-35, 1985

• Ann.E Tylor, A.E.Lang.J.A.Sant-cyr: Frontal lobe dysfunction in Parkinson’s disease the cortical focus of Neostriatal out flow, Brain Journal of Neurology (Oct 1986)

• Anthony.S, Fauci M.D), E ugene Braunwald, Kurt J. Jean D, Joseph B, Martin, Dennis Kasper, Stephen L- Harrison's Principle of Internal medicine 14th edition 1998. Mcgraw-Hill, Health profession division printed in Singapore.

• Basvarajiyam: - By Basavraj, Ed and Pub. By Rajeshwar Datt, Shastry, Chalikhambha sanskrit series, varanasi 1987.

• B. K. Mahajan :- Methods in Biostatistics, Sixth Edition, Published by Jaypee Brothers Medical publishers Pvt. Ltd., B -3 Emca House, 23/ 23B Ansari road, DaryaganJ post Box 7193, New Delhi 110002, India.

• Bhavamisra :- Bhava prakasa with Vidyotini, Hindi Commentary by Brahmasankar Shastri Chaukhambha Sanskrit Series, Banaras (1956),

• Bouldue Helens L, Marcelo, Paulal robert, Robinson's Sergio E, Starkstein, Thomas: Depression and cognitive impairment in Parkinson's disease. Annual of Neurology, 1989

• Caraka Samhita :- Agnivesh Revised by Caraka and Dridhabala, Vidyotini Hindi commentary by pt. Kashinath shastri and Dr. Gorakh Nath Chaturvedi - 13th edition 1986, Chaukhambha Sanskrit series Varanasi.

• Caraka Samhita :- Gulabkunverba Ayurveda Society, Jamnagar

• Caraka Samhita :- Charaka Samhita with English translation of Chakrapani commentary. By Bhagwan Dash, Chhaukhambha Sanskrit series, Varanasi.

• Caroline M. Tanner (MD, M.P.H. ), Samul. G. Goldman: Epidemiological of Parkinson’s disease from the Parkinson’s Institute, Sunnyvale, California – U.S.A. Neurological clinic

• Annual of Neurology - May 1996.

• Caroline M. Tanner (MD, M.P.H. ), Samul. G. Goldman: Epidemiological of Parkinson’s disease from the Parkinson’s Institute, Sunnyvale, California – U.S.A. Neurological clinic

• Annual of Neurology - May 1996.

• Cotzias AC, Papavasiliou PS, Gellene R:- modification of Parkinsonism - chronic treatment with L - dopa - New England Journal of medicine - 1969 ; 280 : 337 - 45.

• Dhurve Sanjay A and Gurdip singh: A clinical study on Kampa-Vata (Parkinson’s disease) and its management with Kapikacchu (Mucuna pruriens). MD (Ayu) Thesis IPGT&RA, GAU Jamnagar (2001)

• Goodman and Gilman’s:- The pharmacological Basis of therapeutics- 7th edition Macmillan publishing company (New York, U.S.A).

• Govind Das:- Bhasjya Ratnavali with chandraprabha commentary, Edited by Vaidya Lal Chandraj 8th Edition, Motilal Banarasidas Delhi (1997)

• Jankovic, j. (ed) (1994): Movement disorders, in neurological clinics vol. 2.pp 415 - 634 w.b. Sunders, Philadelphia.

• Sharma P. V. (1988):- Dravyaguna Vigyana, Chaukhambha Surbharti Academy, Varanasi.

• Sharangadhara:- Sharangadhar Samhita Edited by Siddhinandan Mishra, 1st Edition, Chaukhambha oriental, Varanasi.

• Shivram Krishnam & Singh Gurdip: A study on Ayurved management of sakampa pakshagvata (Paralysis agitans) P. G. thesis, 1989, I.P.G.T. & R. A. Jam.

• Slegfried:- J. European Neurology 1987; 27(Suppl.C) 98-104.

• Sodhala :- Gada Nigraha, Chaukhambha Sanskrit series, Varanasi (1964)

• Susruta: Susruta Samhita with Ayurveda Tatva sandipika, Hindi commentary by shastri A, Chaukhambha Sanskrit Sansthan, Varanasi


Refbacks

  • There are currently no refbacks.